Sheep in Wolf’s Clothing: Pedunculated Colonic Lipoma with Overlying Hyperplastic and Ulcerated Epithelium
Lipomas are the most common non-epithelial benign tumors of the gastrointestinal tract with a reported incidence in the colon of 0.2–4.4%. These lesions are usually asymptomatic with a typical endoscopic finding of a smooth, slightly yellow, circular, polyp that is sessile in most cases, covered with normal colonic mucosa.
From the Laboratory Bench to the Patient’s Bedside: An Update on Clinical Trials With Mesenchymal Stem Cells
The microenvironment of mammalian bone marrow is composed of several different elements that support hematopoiesis and bone homeostasis (Muller-Sieburg and Deryugina, 1995; Zhang et al., 2003). It includes a heterogeneous population of cells...
Hepatic hematoma is a rare but possible complication of ERCP. We describe the case of a 75-year old man with a large, 8 × 12 cm, sub-capsular and intra-parenchymal hematoma post ERCP, affecting the right liver segments and treated conservatively.
Since the first human liver transplant performed in 1963 by Thomas Starzl, many advances in surgical techniques and immunosuppressive therapy have helped to increase the numbers of women who undergo allogenic organ transplantation each year ...
Update on Chronic Rejection After Intestinal Transplant: An Overview From Experimental Settings to Clinical Outcomes
Chronic rejection affects the long-term survival of solid-organ transplants, accounting for an incidence of between 5% and 10% after intestinal/multivisceral transplant. Because of unclear symptoms and signs and endoscopic findings, the diagnosis is ...
The question of whether health care inequities occur before patients with end-stage liver disease (ESLD) are waitlisted for transplantation has not previously been assessed. To determine the impact of gender, race and insurance on access to ...
In June 2001, a 17-year-old girl was involved in a high-speed motorcycle crash. She was taken to a local hospital, where multiple large, actively bleeding lacerations of the spleen and right lobe of the liver were found. A splenectomy was performed and...
ITALIAN SCIENTISTS HAVE LONG LAMENTED THE lack of resources, political attention, and meritocracy in assigning taxpayers’ money...
Three decades of illegal practices of waste dumping and consequent environmental abuse have made the Campania Region, Southern Italy, a unique case in the context of wasterelated health outcomes. Scientific evidence is mounting in support of a ...
Immunosuppression has been sporadically discontinued by noncompliant liver allograft recipients for whom an additional 4 1/2 years of follow-up is provided
Umpredictable scientific research n.2: Effect of Donor Age and Sex on the Outcome of Liver Transplantation
We correlated donor and recipient factors with graft outcome in 436 adult patients who underwent 462 liver transplants. Donor variables analyzed were age, gender, ABO blood group, cause of death, length of stay in the intensive care unit...
Umpredictable scientific research n.1: Treatment of Hepatic Epithelioid Hemangioendothelioma With Liver Transplantation
Ten patients received liver transplants for unresectable epithelioid hemangioendothelioma (EHE). At the time of transplantation, four patients had microscopic metastases to the hilar lymph nodes, and one of the four also had metastases to a ...
Organ transplantation is one of the most remarkable therapeutic advances in modern medicine; it started as an experiment and has become a life-saving practice. We briefly describe the major milestones of this multidisciplinary clinical science...
Healthcare systems vary consistently between countries but most are facingsimilar challenges. The changing medical, demographic, technologicalconditions and the impact of financial and economic austerity create newdemands at a time when the public are...
Immunosuppression, Compliance, and Tolerance After Orthotopic Liver Transplantation: State of the Art
Orthotopic liver transplantation is the treatment of choice for several otherwise irreversible forms of acute and chronic liver diseases. Early implemented immunosuppressant regimens have had disappointing results with high rejection rates. However ...
Eight years ago we published this commentary, which unfortunately remains sadly topical. Recent events have confirmed that it is urgent and necessary to adopt forward-looking visions rather than deal with emergency solutions.
Management of benign liver tumors represents still an open debate, with no clear guidelines for patient selection, treatment options, and indications to surgical intervention. Usually, most of these diseases are conservatively treated, in view of their lo
I thought to post a few of our scientific manuscripts to share this important innovative procedure that will help thousands of patients suffering from end-stage kidney disease.
A doctor’s conduct in his clinical activity, his relationship with the patient, not only serve as a role model for new generations but are all elements that make up his way of being a doctor and they are inevitably influenced by his human nature.
30 years ago the first baboon-to-human transplant, with my mentor T. E. Starzl. I would like to recall this historic article in the journal "The Lancet" of 9 January 1993
Delmonico and Ascher respond to Rees et al, but also to a confidential letter of intent, a work-in-progress draft for a possible grantapplication, which is not a public document and was never meant for distribution. We ask how they would respond ...
Ignazio Marino was born in Genoa, Italy, in 1955 as the son of a naval engineer. His interest in medicine, in particular surgery, began while attending high school as a mean to ‘‘achieve tangible results and life-changing out-comes on patients ...
KRIPKE TAKES ISSUE WITH THE REFERENCES we cited in our Policy Forum. We based our arguments on a thorough analysis of many reports and communications of all the institutions we discussed, including Oxfam’s (1). For example, a substantive 2008 ...